The Cerebral Vasomotor Reactivity (VMR) test using Transcranial Doppler (TCD) is a valuable tool in assessing cerebrovascular health, guiding treatment decisions, and predicting stroke risk. It is particularly useful in the evaluation of stroke, carotid disease, traumatic brain injury, vascular dementia, and endothelial dysfunction. Given its non-invasive nature and real-time results, it remains a powerful diagnostic and prognostic tool in neurology, stroke medicine, and critical care.